GPBAR-A

Code: SML1207-5MG D2-231

Biochem/physiol Actions

GPBAR-A is a very potent agonist of the bile acid receptor GPBA (also known as TGR5). In murine primary intestinal cultures, GPBAR-A induces an elevat...


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€145.96 5MG
€179.53 inc. VAT
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Biochem/physiol Actions

GPBAR-A is a very potent agonist of the bile acid receptor GPBA (also known as TGR5). In murine primary intestinal cultures, GPBAR-A induces an elevation in intracellular cAMP and calcium levels, and stimulates secretion of GLP-1.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyZIXNJVGTAXRKAP-UHFFFAOYSA-N
InChI1S/C23H15F7N2O2/c24-19-4-2-1-3-17(19)16-5-6-31-21-18(16)11-32(20(33)12-34-21)10-13-7-14(22(25,26)27)9-15(8-13)23(28,29)30/h1-9H,10-12H2
Quality Level100
SMILES stringO=C(CO1)N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)CC3=C1N=CC=C3C4=C(F)C=CC=C4
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number877052-79-4
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