U-104, >=98% (HPLC)

Code: SML0374-5MG D2-231

Biochem/physiol Actions

U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growt...


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€96.78 5MG
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Biochem/physiol Actions

U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyYJQZNWPYLCNRLP-UHFFFAOYSA-N
InChI1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18)
Quality Level100
SMILES stringO=C(NC1=CC=C(S(N)(=O)=O)C=C1)NC2=CC=C(F)C=C2
solubilityDMSO: >15 mg/mL
storage temp.2-8°C
Cas Number178606-66-1
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