Alosetron hydrochloride, >=98% (HPLC)

Code: SML0346-50MG D2-231

Biochem/physiol Actions

Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric ne...


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€318.90 50MG
€392.25 inc. VAT
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Biochem/physiol Actions

Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... HTR3A(3359)
InChI keyFNYQZOVOVDSGJH-UHFFFAOYSA-N
InChI1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H
Quality Level100
SMILES stringCN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl
solubilityH2O: ≥5 mg/mL at warmed
storage conditiondesiccated
storage temp.2-8°C
Cas Number122852-69-1
Hazard Class6.1
Un Number2811
Pack GroupIII
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