ANTI-CYP3A4 ANTIBODY PRODUCED IN RABBIT+

Code: SAB5700096-100UL D2-231

General description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions inv...


 Read more

Your Price
€326.00 EACH
€400.98 inc. VAT

General description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).

Physical form

PBS with 0.02% sodium azide,pH7.3.

Storage and Stability

Store at 4℃. Avoid freeze / thaw cycles.

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration0.77 mg/ml
formbuffered aqueous solution
Gene Informationhuman ... CYP3A4(1576)
mol wt57
Quality Level100
shipped inwet ice
species reactivityhuman, rat, mouse
storage temp.2-8°C
technique(s)western blot: 1:500-1:1000, immunofluorescence: 1:20-1:100, immunohistochemistry: 1:20-1:50
UniProt accession no.P08684
This product has met the following criteria to qualify for the following awards:



HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.