Application

Human IL-8 /CXCL8 ELISA Kit has been used:to quantify IL?8 from A549 cell culture mediumin quantitative measurement of IL-8 from cell culture supernatantin supernates of acute lung infection model (ALIM)

Biochem/physiol Actions

Interleukin-8 (IL-8)/CXCL8 participates in the progression of peripheral muscle weakness in individuals with COPD (chronic obstructive pulmonary disease). It helps in the transport of neutrophils across endothelium, pulmonary epithelium and fibroblasts.

General description

Interleukin-8 (IL-8)/CXCL8 is an important chemoattractant cytokine and activator of neutrophils. It is liberated from endothelial cells, gingival fibroblasts, neutrophils, monocytes and phagocytes in the gingival crevice. IL-8 belongs to the CXC subfamily. This gene is located on human chromosome 4q13.3.

Immunogen

Recombinant Human IL-8

Other Notes

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