Reserpine,

Code: R0875-1G D2-231

Application

Reserpine has been used:to study its effect on minimal inhibitory concentration of trovafloxacin and ciprofloxacininject rats, to study its effect on behavioural ...


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Your Price
€259.90 1G
€319.68 inc. VAT

Application

Reserpine has been used:to study its effect on minimal inhibitory concentration of trovafloxacin and ciprofloxacininject rats, to study its effect on behavioural parameters such as locomotion and fear/anxietyas a lock spray reference compound in lipid profiling

Biochem/physiol Actions

Reserpine is an alkaloid present in Rauwolfia species. It is useful in treating systemic hypertension, schizophrenia, psychiatric disorders and Raynaud′s syndrome. Reserpine is known to inhibit adrenaline induced-cutaneous blood vessel constriction. It diminishes the effect of hyperthyroidism on cardiovascular and nervous system.

Inhibits vesicular uptake of catecholamines and serotonin.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1 g in glass bottle

Gene Informationhuman ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC18A2(6571)
InChI keyQEVHRUUCFGRFIF-MDEJGZGSSA-N
InChI1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
mp~265 °C (dec.)
Quality Level200
SMILES stringCO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6
Cas Number50-55-5
This product has met the following criteria to qualify for the following awards:



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