Features and Benefits
DBCO-dPEG ®₁₂-MAL can be used to conjugate two different proteins or an antibody with a payload by using copper-free "click" chemistry with the DBCO and reaction of the maleimide with a free thiol.
General description
DBCO-dPEG®12-MAL is a versatile heterobifunctional cross-linking reagent used in strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This approach is also known as copper-free click chemistry. The presence of maleimidopropyl (MAL) functional group in the reagent forms a thiol-ether linkage with sulfhydryl groups.
Legal Information
dPEG is a registered trademark of Quanta BioDesign
Products Protected under U.S. Patents # 7,888,536 B2
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