Features and Benefits

The azido-dPEG^®₈-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer(32.2 Å) and a reactive group (NHS ester) on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily react with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

dPEG is a registered trademark of Quanta BioDesign

Products Protected under U.S. Patents # 7,888,536 B2