BIOTIN-DPEG 4-TFP ESTER

Code: QBD10009-1000MG D2-231

Application

Biotin-dPEG®4-TFP ester is an amphiphilic and hydrolytically stable compound used as a cross-linking reagent in biotinylations reaction...


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€935.00 EACH
€1,150.05 inc. VAT
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Application

Biotin-dPEG®4-TFP ester is an amphiphilic and hydrolytically stable compound used as a cross-linking reagent in biotinylations reactions.

Features and Benefits

Biotin-dPEG®4-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyzes more slowly than NHS ester in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®4-TFP ester has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. The PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Legal Information

dPEG is a registered trademark of Quanta BioDesign

Products Protected under U.S. Patents # 7,888,536 B2

assay>90%
formsolid or viscous liquid
polymer architectureshape : linearfunctionality : monofunctional
reaction suitabilityreagent type: cross-linking reagent, reaction type: Biotinylations, reaction type: Biotinylationsreactivity: amine reactive
shipped inambient
SMILES stringO=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O
storage temp.−20°C
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