PF-06745268

Code: PZ0391-5MG D2-231

Biochem/physiol Actions

PF-06745268 is an orally available, brain penetrant, potent and selective γ-secretase modulator. PF-06745268 induces robust and sustained reducti...


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€68.63 5MG
€84.41 inc. VAT
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Biochem/physiol Actions

PF-06745268 is an orally available, brain penetrant, potent and selective γ-secretase modulator. PF-06745268 induces robust and sustained reduction of brain amyloid-β42 (Aβ42) in rats.

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Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

assay≥98% (HPLC)
colorwhite to beige
formpowder
manufacturer/tradenamePfizer®
optical activity[α]/D -13 to -17°, c = 1.0 in methanol
originatorPfizer
SMILES stringO=C1C(N2C=C(N=C2)C)=CC=C3N1CCN(C[C@@]4(C5)[C@@]5([H])C(C)(C)OC6=C4C=C(C(F)(F)F)C=C6)C3=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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