PHA-408

Code: PZ0266-25MG D2-231

Biochem/physiol Actions

PHA-408 is a potent, selective I kappa B-kinase 2 (IKK-2) inhibitor. PHA-408 is a tight binding, ATP competitive IKK-2 inhibitor with greater than 350...


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Your Price
€380.00 25MG
€467.40 inc. VAT

Biochem/physiol Actions

PHA-408 is a potent, selective I kappa B-kinase 2 (IKK-2) inhibitor. PHA-408 is a tight binding, ATP competitive IKK-2 inhibitor with greater than 350-fold selectivity for IKK-2 vs IKK-1 (IC50 values of 10-40 nM at IKK-2 vs 14 µM at IKK-1). PHA-408 was shown to suppress inflammatory cellular events, and to reduce inflammation in animal models of arthritis.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Other Notes

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
manufacturer/tradenamePfizer®
originatorPfizer
Quality Level100
shipped indry ice
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number503555-55-3
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