Application

p-Phenylenediamine has been used:to evaluate its sensitization potential in vitro in langerhans-like dendritic cells and autologous T cellsto treat the dorsal sides of the ears of mice, to study its systemic immunological effectsin glycerol to coverslip coronal sections in the attempt to count Aβ plaquesAnti-fade reagent is added to the mounting medium in fluorescence microscopy to retard photobleaching of fluorescein and other fluorescent dyes.

Biochem/physiol Actions

p-Phenylenediamine causes allergic reactions with skin. It is widely used in hair dyes. It eventually forms Bandrowski′s base, which is found to be the primary cause for allergy. p-Phenylenediamine exposure results in dermatitis, urticaria and anaphylaxis. It acts as an electron donor and is known to reduce cytochrome c.

Caution

Darkens in storage.

Packaging

1 kg in glass bottle

50, 100, 250 g in glass bottle