Exo 1, >=98% (HPLC), solid

Code: E8280-5MG D2-231

Application

Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to...


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€53.62 5MG
€65.95 inc. VAT
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Application

Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to study its effects on the longinterspersednuclearelement-1 (L1) retrotransposition.

Biochem/physiol Actions

Reversible inhibitor of exocytosis; Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator.

Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
formsolid
InChI keyKIAPWMKFHIKQOZ-UHFFFAOYSA-N
InChI1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18)
Quality Level100
SMILES stringCOC(=O)c1ccccc1NC(=O)c2ccc(F)cc2
solubilityDMSO: soluble 19 mg/mL
Cas Number75541-83-2
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