Cyclopamine hydrate, >=98% (HPLC)

Code: C4116-1MG D2-231

Application

Cyclopamine hydrate has been used:as a sonic hedgehog (Shh) inhibitor in various experimentsto explore the effects of stress stimulation on the proliferation and ...


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€331.30 1MG
€331.30 inc. VAT
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Application

Cyclopamine hydrate has been used:as a sonic hedgehog (Shh) inhibitor in various experimentsto explore the effects of stress stimulation on the proliferation and differentiation of fibrochondrocytesto study its influence on ocular vessel patterning

Biochem/physiol Actions

Cyclopamine is a Hedgehog signaling pathway inhibitor; inhibits the growth of medulloblastoma cells.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

General description

Cyclopamine is a steroidal alkaloid, extracted from Veratrum californicum. It prevents tumor cell growth and invasiveness in vitro and in vivo.

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formsolid
Gene Informationhuman ... EBP(10682)
InChI keyKDAGJRDPNXDDSB-HBYCUIHISA-N
InChI1S/C27H41NO2.H2O/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2;/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3;1H2/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-;/m0./s1
Quality Level100
SMILES stringO.C[C@@H]1CN[C@H]2[C@@H](C)[C@@]3(CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C)O[C@@H]2C1
solubilityDMSO: soluble ≥5 mg/mL, H2O: insoluble
storage temp.2-8°C
Cas Number4449-51-8
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