Application
1-Hydrosilatrane is an air- and moisture-stable hydride reducing reagent that exhibits high functional group compatibility. The Adler group has used 1-hydrosilatrane for the reduction of ketones and aldehydes as well as the direct reductive amination of ketones under mild conditions.
Other Notes
Chiral Bronsted Acid-Catalyzed Metal-Free Asymmetric Direct Reductive Amination Using 1-HydrosilatraneSilatrane as a Practical and Selective Reagent for the Reduction of Aryl Aldehydes to Benzylic Alcohols
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