Application

2,3,7,8-Tetrafluorothianthrene-S-oxide (TFT S-oxide) is a fluorinated sulfoxide-based thianthrene reagent for late-stage C-H functionalization. Developed by the Ritter Lab, C-H functionalization by thianthrenation with TFT S-oxide proceeds with >99% selectivity and furnishes functionalized arenes serving as synthetic linchpins for further participation in diverse transformations.The nonfluorinated thianthrene S-oxide is also available as catalog# 903973 for all arenes more electron-rich than anisole.

Legal Information

Patent Application EP18204755.5 This product is manufactured pursuant to a license with Studiengesellschaft Kohle mbH

Other Notes

Site-selective and versatile aromatic C-H functionalization by thianthrenationVideo: Site-selective C-H functionalization by thianthrenationIn the Pipeline: New Chemistry, Making New Things