Application

MCAT-53 is a recyclable ruthenium-containing catalyst for C–C coupling reactions in aqueous conditions. In contrast to Pd-catalyzed reactions, MCAT-53 achieves C–H-activated C–C coupling in water under ligand-free conditions, requiring no co-solvent, surfactant, or additional steps for activation. Bench- and air-stable, MCAT-53 will find wide utility in cost-effective and greener alternatives in pharmaceutical and manufacturing processes. This water-friendly catalyst is offered in collaboration with Chicago Discovery Solutions.The catalyst has been successfully employed to synthesize a key intermediate of anacetrapib as a single regioisomer.

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Legal Information

MCAT-53 is a trademark of Chicago Discovery Solutions LLC

Other Notes

Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond ActivationMCAT-53^™: A Green Ruthenium Catalyst for Cross-Coupling & C–H Activation

Packaging

1 g in glass bottle

250 mg in glass bottle