Biochem/physiol Actions

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

General description

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Packaging

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)