18:1 LYSO PG

Application

18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.

General description

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.

Packaging

5 mL Clear Glass Sealed Ampule (858125C-500mg)