Application

20:4 PE has been used as an antigen in enzyme linked immunosorbent assay (ELISA) for detecting antiphosphatidylethanolamine (aPE) antibodies. It is suitable for use as an internal standard for electrospray ionization-mass spectrometry (ESI-MS), high performance liquid chromatography and in the preparation of lysophosphatidylethanolamine.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) is implicated in a numerous function like membrane fusion, cell cycle, autophagy, apoptosis, and cognitive function. 20:4 phosphatidylethanolamine (PE)/ DAPE induces cell death in malignant pleural mesothelioma (MPM) cells. DAPE enhances protein phosphatase 2A (PP2A) and protein tyrosine phosphatase 1B (PTB1B) activity.

General description

Phosphatidylethanolamine (PE) is a membrane phospholipid and the types depend on the combination of free fatty acids on the α and β position. 20:4 PE has arachidonic acid on the α and β positions.

Packaging

5 mL Clear Glass Sealed Ampule (850800C-25mg)