22:6 PE

Application

22:6 PE has been used as a standard for the optimization of liquid chromatography-mass spectrometry (LC/MS) conditions and to detect the serum antiphosphatidylethanolamine (aPE) antibodies from patients using enzyme linked immunosorbent assay (ELISA). It is suitable for use in testing the effect of increasing acyl chain unsaturation on phase separation from the lipid raft molecules spingomyelin (SM) and cholesterol (CHOL).

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a key role in membrane fusion, cell cycle, autophagy, apoptosis, and cognitive function.

General description

22:6 PE is a polyunsaturated homoacid. Phosphatidylethanolamine (PE) is a membrane phospholipid. The types of PE depends on the combination of free fatty acids on the α and β position. 22:6 PE denotes the length of the carbon chain:degree of unsaturation in the PE.

Packaging

5 mL Clear Glass Sealed Ampule (850797C-25mg)