Application

4ME 16:0 PC is suitable for use:to study its phase behaviour and its interactions with the representativeantimicrobial peptide PGLa fromXenopus laevis(peptidyl-glycylleucine-carboxyamideto improve the mechanical stability of planar lipid bilayer membraneto prepare giant unilamellar vesicles (GUVs)

Biochem/physiol Actions

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine can be used as a bilayermimic for electrophysiological measurements. It is stable under mechanical stress but the esterlinkages are liable to hydrolysis under acidic or alkaline conditions.

General description

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine is a synthetic lipid. It has esterlinkagesbetween acyl chains andglycerolbackbone and also between the headgroup and glycerol backbone. This neutral lipids possess high steric asymmetry. It remains in fluid or viscous liquid crystalline state over a wide range oftemperature.

Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis.

Packaging

5 mL Clear Glass Sealed Ampule (850356C-200mg)

5 mL Clear Glass Sealed Ampule (850356C-25mg)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850356C-500mg)