Application

16:0-18:1 Phosphatidylethanol is suitable for use in the preparation of liposomes used forpermeabilitystudies.

Biochem/physiol Actions

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

General description

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group. It is widely distributed in gram-positive organisms.

Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

Packaging

5 mL Clear Glass Sealed Ampule (840514C-25mg)