08:0 PA

Code: 830842P-10MG D2-231

Application

08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian...


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Your Price
€231.90 10MG
€285.24 inc. VAT

Application

08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian target of rapamycin (mTOR) pathway signaling.

Biochem/physiol Actions

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 08:0 PA/C8-PA has the ability to affect the phosphorylation of mammalian target of rapamycin (mTOR) and the viability of gallbladder carcinoma cells, that are treated with histone deacetylase inhibitors (HDACIs).

General description

Phosphatidic acidis obtained from glycerophospholipid with the help of phospholipase D. 08:0 PA/1,2-dioctanoyl-sn-glycero-3-phosphate (C8-PA) is an mammalian target of rapamycin (mTOR) activator.

Packaging

5 mL Clear Glass Sealed Ampule (830842P-25mg)

5 mL Clear Glass Sealed Ampule (830842P-10mg)

assay>99% (TLC)
formpowder
manufacturer/tradenameAvanti Polar Lipids 830842P
packagingpkg of 1 × 25 mg (830842P-25mg), pkg of 1 × 10 mg (830842P-10mg)
shipped indry ice
SMILES string[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]
storage temp.−20°C
Cas Number321883-54-9
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