Biochem/physiol Actions

Primary Targetinitiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code

General description

Antibiotic effective against Gram-positive and Gram-negative bacteria. Often used in culture media to control growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code.

Antibiotic effective against gram-positive and gram-negative bacteria. Often used in culture media to control the growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code. Suggested working concentration: 25-50 µg/ml.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Lech, K. and Brent, R. 1995. in Current Protocols in Molecular Biology, Vol. 1 (Ausubel, F.M., et al., eds.), John Wiley & Sons, New York Unit 1.4.Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York, p. A.6.Modolell, J. and Davis, B.D. 1969. Nature224, 345.

Packaging

100 g in Glass bottle

Preparation Note

Autoclaved media should be cooled to ≤55°C before adding streptomycin.

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Carcinogenic / Teratogenic (D)