General description
A cell-permeable, thiadiazole-pyridazine compound that acts as an inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC50 of 2.3 nM. In vivo, it exhibits an ED50 of 1-3 mg/kg, p.o., in mouse liver PD assays.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Leger, S., et al. 2010. Bioorg Med Chem Lett.2, 499.
Packaging
10 mg in Glass bottle
Warning
Toxicity: Standard Handling (A)
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