PKC# TRANSLOCATION INHIBITOR 1PC X 5MG

Code: 539522-5MG D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: yes

Product does not compete with ATP.

Primary TargetPKCε Translocation

General de...


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€326.10 EACH
€401.10 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: yes

Product does not compete with ATP.

Primary TargetPKCε Translocation

General description

An octapeptide that selectively inhibits the translocation of PKCε to subcellular sites. Inhibition of PKCε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes.

An octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sold under license of U.S. Patent 5,783,405.

Other Notes

Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.

Packaging

5 mg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.

Sequence

H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH

Warning

Toxicity: Standard Handling (A)

assay≥97% (HPLC)
colorwhite
formlyophilized solid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitywater: 3 mg/mL
storage conditiondesiccated (hygroscopic), OK to freeze
storage temp.2-8°C
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