Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetNitric oxide radical scavenger

General description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner, without affecting nitric oxide synthase activity. Inhibits enhanced vascular permeability in solid tumors.

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Hogg, N., et al. 1995. Free Radic. Res. 22, 47.Maeda, H., et al. 1994. Jpn. J. Cancer Res.85, 331.Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.Akaike, T., et al. 1993. Biochemistry32, 827.

Packaging

25 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.

Warning

Toxicity: Irritant (B)