Biochem/physiol Actions
Primary TargetmGlu2 & mGlu3
General description
A potent agonist for group II metabotropic glutamate receptors (EC50 = 0.49 µM and 0.44 µM for mGlu2 and mGlu3, respectively). Higher level of activity than glutamate or (±)-trans-ACPD. Widely used in studies related to neurotransmissions mediated via group II mGlu receptors.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Shinozaki, H., et al. 1989. Br. J. Pharmacol.98, 1213.Hayashi, Y., et al. 1992. Br. J. Pharmacol.107, 539.Nakanishi,S. 1992. Science.258, 597.Watkins, J., et al. 1994. Trends Pharmacol Sci.15, 333.Schoepp, D.D., et al. 1999. Neuropharmacology.38, 1431.
Packaging
5 mg in Glass bottle
Warning
Toxicity: Standard Handling (A)
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