MDL-12;330A; Hydrochloride

Biochem/physiol Actions

Reversible: no

Primary TargetAdenylate cyclase

Product does not compete with ATP.

Target IC₅₀: 250 µM against adenylate cyclase

Cell permeable: yes

General description

Cell-permeable and irreversible inhibitor of adenylate cyclase (IC₅₀ = 250 µM).

Cell-permeable irreversible inhibitor of adenylate cyclase (IC₅₀ = 250 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Correia-de-Sa, P., and Ribeiro, J.A. 1994. Eur. J. Pharmacol. 271, 349.Gorczynska, E., et al. 1994. Endocrinology134, 293.Delpiano, M.A., and Acker, H. 1991. J. Neurochem.57, 291.Lippe, C., and Ardizzone, C. 1991. Comp. Biochem. Physiol.99, 209.Guellaen, G., et al. 1977. Biochim. Biophys. Acta 484, 465.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Warning

Toxicity: Standard Handling (A)