Propionyl-L-carnitine,>=97.0% (TLC)

Code: 42602-50MG D2-231

Application

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

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Application

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

General description

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

assay≥94.0% (HPLC)
colorwhite to off-white
formpowder or crystals
impurities≤10% water (calcd. from elemental analysis)
InChI keyUFAHZIUFPNSHSL-MRVPVSSYSA-N
InChI1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
optical activity[α]/D -23±3°, c = 1 in H2O
Quality Level100
SMILES string[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
storage temp.2-8°C
technique(s)LC/MS: suitable
Cas Number21064-69-7
This product has met the following criteria to qualify for the following awards:



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