Biochem/physiol Actions
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Targetmannosidase-1
General description
A potent alkaloid inhibitor of mannosidase I. Does not affect mannosidase II and the endoplasmic reticulum α-mannosidase.
A potent alkaloid inhibitor of mannosidase I. An ineffective inhibitor of mannosidase II and the endoplasmic reticulum α-mannosidase.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Weng, S., and Spiro, R.G. 1996. Arch. Biochem. Biophys.325, 113.Kayakiri, H., et al. 1991. Chem. Pharm. Bull. 39, 1378.Elbein, A.D., et al. 1990. J. Biol. Chem. 265, 15599.Iwami, M., et al. 1987. J. Antibiotic. 40, 612.
Packaging
1 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Warning
Toxicity: Standard Handling (A)
This product has met the following criteria to qualify for the following awards: