Biochem/physiol Actions

Primary TargetPKCβ

Reversible: yes

Product does not compete with ATP.

Cell permeable: yes

Target IC₅₀: 2 µM against PKCβ

General description

A potent, cell permeable, and reversible inhibitor of protein kinase C_β isoform (PKC_β; IC₅₀ = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.

A potent, cell permeable, and reversible inhibitor of protein kinase Cβ isoform (PKC_β; IC₅₀ = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Gonindard, C., et al. 1997. Cell Biol. Toxicol. 13, 141.

Packaging

2 mg in Plastic ampoule

Packaged under inert gas

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)