Diethyl Pyrocarbonate

Code: 298711-100GM D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetInhibits ryanodine binding to ryanodine/Ca2+ rece...


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€546.58 100GM
€672.29 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle

General description

Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.

Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Shoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.Blumbers, D.O. 1987. Methods Enzymol. 152, 20.

Packaging

100 g in Glass bottle

25 g in Plastic ampoule

Warning

Toxicity: Harmful (C)

assay≥97% (titration)
colorclear colorless
formliquid
InChI keyFFYPMLJYZAEMQB-UHFFFAOYSA-N
InChI1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitychloroform: soluble, ethanol: soluble
storage conditionprotect from light, OK to freeze
storage temp.2-8°C
Cas Number1609-47-8
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