MG Daidzein 1PC x 25MG

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Target IC₅₀: 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively

Primary TargetMiaPaC-2, PANC-1

General description

Inactive analog of genistein (Cat. No. 345834). Blocks the G₁ phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC₅₀ >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC₅₀= 45 µM and 75 µM, respectively).

Inactive analog of Genistein (Cat. No. 345834). Blocks the G₁ phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC₅₀= 45 µM and 75 µM, respectively).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Guo, J-M., et al. 2004. World J. Gastroenterol.10, 860.Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.

Packaging

Packaged under inert gas

25 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.

Warning

Toxicity: Irritant (B)