Application
Ceramide is used to investigate effects on programmed cell death (apoptosis) and insulin signaling.
Biochem/physiol Actions
Ceramide is a minor component of cell membranes. Activates atypical protein kinase C (e.g., PKCzeta) .
Other Notes
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Preparation Note
from cerebrosides by a modification of the procedure by H.E. Carter et al., J. Lipid Res. 2, 228 (1961)
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