Caspase-9 Inhibitor III

Biochem/physiol Actions

Primary Targetcaspase-9

Reversible: no

Product does not compete with ATP.

Cell permeable: yes

Target IC₅₀: 70 nM against caspase-9

General description

A potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).

A potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197.

Packaging

1 mg in Plastic ampoule

Sequence

Ac-Leu-Glu-His-Asp-CMK

Warning

Toxicity: Standard Handling (A)