Calpain Substrate II; Fluorogenic

Code: 208731-25MG D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetCalpain -1 and -2

General descripti...


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€251.55 EACH
€309.41 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetCalpain -1 and -2

General description

Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 µM, depending on assay conditions.

Fluorogenic substrate for the quantitative determination of porcine calpain I and II activity. Also serves as a substrate for other proteases including proteasome. (excitation wavelength: 380 nm; emission wavelength: 460 nm)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Seol, J.H., et al. 1989. FEBS Lett. 247, 197.Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.Sasaki, T., et al. 1984. J. Biol. Chem.259, 12489.

Packaging

25 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sequence

Suc-Leu-Tyr-AMC

Warning

Toxicity: Standard Handling (A)

assay≥95% (TLC)
coloroff-white
fluorescenceλex ~380 nm, λem ~460 nm
formsolid
InChI keyVSWNAJAOJZXWBM-FTJGSZSVSA-N
InChI1S/C29H33N3O8/c1-4-16(2)27(32-24(34)11-12-25(35)36)29(39)31-22(14-18-5-8-20(33)9-6-18)28(38)30-19-7-10-21-17(3)13-26(37)40-23(21)15-19/h5-10,13,15-16,22,27,33H,4,11-12,14H2,1-3H3,(H,30,38)(H,31,39)(H,32,34)(H,35,36)/t16?,22?,27-/m0/s1
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilityDMSO: soluble
storage conditiondesiccated, protect from light, OK to freeze
storage temp.−20°C
Cas Number94367-20-1
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