General description

A water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 minutes. TCEP is also capable of functioning as a reducing agent even in the pH range of 1.5-8.5. It is more resistant to air-oxidation as compared to DTT.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Getz, E.B., et al. 1999. Anal. Biochem. 273, 73.Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.Burns, J.A., et al. 1991. J. Org. Chem.56, 2648.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Packaging

5 g in Glass bottle

Packaged under inert gas

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). TCEP retains stability when stored at an acidic or alkaline pH; avoid storage at pH 7.0-8.0. Also avoid exposure to high concentrations of phosphate ions (>150 mM). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Corrosive (L)