Suz-12; Ms x 3C1.2-100ug

Analysis Note

ControlHeLa cell lysate

Application

Research CategoryEpigenetics & Nuclear Function

Anti-SUZ12 Antibody, clone 3C1.2 is a high quality Mouse Monoclonal Antibody for the detection of SUZ12 & has been validated in WB.

Research Sub CategoryChromatin Biology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Component of the PRC2 complex, which methylates ′Lys-9′ and ′Lys-27′ residues of histone H3.

Immunogen

Full length, recombinant human SUZ12.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Protein A purified

100 µg of Protein A purified mouse monoclonal IgG1κ in 100 µL of 1X PBS, pH 7, 0.1% Azide.

Format: Purified

Quality

Routinely evaluated by immunoblot.

Specificity

SUZ12

Storage and Stability

2 years at -20°C from date of shipment.

Target description

95 kDa