In contemporary research, human-induced pluripotent stem cells (hiPSCs) have emerged as vital tools for disease modelling and therapy development. Despite their immense potential, challenges persist in the cultivation of hiPSCs, particularly concerning technical considerations such as cell sourcing, maintenance, quality control, and study design, all intertwined with cost considerations.
Notably, the demanding nature of daily media changes also stands out as a significant obstacle in iPSC culture. In response to these challenges, researchers have been actively exploring alternatives to enhance the efficiency and cost-effectiveness of iPSC culture techniques.
A breakthrough study now introduces FGF-2 STAB®, the thermostable version of FGF-2, as a promising solution to revolutionise iPSC culture techniques.
Revolutionising iPSC Culture with FGF-2 STAB®:
Sourced from Core Biogenesis, FGF-2 STAB® stands out as the sole plant-derived B® version, offering an endotoxin-free expression system and delivering an animal-free, tag-free protein. These distinctive features not only ensure stability and cost-effectiveness but also promote sustainable practices in stem cell research and manufacturing. By harnessing environmentally responsible manufacturing processes for recombinant proteins in plant systems, Core Biogenesis sets a new standard for ethical and eco-friendly biotechnology.
Key Highlights of FGF-2 STAB®:
- Enhanced iPSC Culture Quality: FGF-2 STAB® facilitates superior quality iPSCs cultures, promoting high cell proliferation rates while maintaining a stable pluripotent phenotype.
- Streamlined Feeding Schedules: Consistent signalling levels of FGF-2 STAB® enable the adoption of optimised cell feeding schedules, aligning with weekend-free iPSC culture protocols and commercial media kits.
- Cost Savings: Core Biogenesis FGF-2 STAB® offers significant cost savings for iPSC research and manufacturing projects, making cutting-edge technology more accessible to the scientific community.
- Environmental Responsibility: By opting for plant-derived FGF-2 STAB®, researchers contribute to reducing environmental impacts associated with stem cell research and manufacturing activities.
Read the full application notes below for detailed insights.