General description
An agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer′s disease and schizophrenia.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Wang, D., et al., 2011. Biochem. Biophys. Res. Commun.410, 229.Si, W., et al., 2010. Neurosci. Lett.473, 115.Stanhope, et al., 2001. J. Exp. Pharmacol. Ther.299, 782.
Packaging
10 mg in Glass bottle
Warning
Toxicity: Standard Handling (A)
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