Biochem/physiol Actions

Primary TargetPKCζ

Cell permeable: no

Reversible: yes

Product does not compete with ATP.

General description

Non-cell-permeable protein kinase C_ζ and protein kinase C_ι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKC_ζ/ι in in vitro kinase assays.

A selective, reversible, and substrate competitive inhibitor of protein kinase C_ζ and protein kinase C_ι (PKC_ζ/ι) isozymes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Sajan, M.P., et al. 1999. J. Biol. Chem.274, 30495.Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.

Packaging

500 µg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

H-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH

Warning

Toxicity: Standard Handling (A)