NVP-ADW742

Code: SML1921-25MG D2-231

Application

NVP-ADW742 has been used as an insulin-like growth factor 1 receptor (IGF1R) inhibitor to test the effects of filamin A (FLNA) silencing in a cell proliferation a...


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€411.00 25MG
€505.53 inc. VAT
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Application

NVP-ADW742 has been used as an insulin-like growth factor 1 receptor (IGF1R) inhibitor to test the effects of filamin A (FLNA) silencing in a cell proliferation assay.

Biochem/physiol Actions

NVP-ADW742 is a potent and selective ATP-competitive inhibitor of Insulin-like growth factor-I receptor (IGF-IR) kinase. NVP-ADW742 sensitizes cancer cell lines to multiple anticancer agents including etoposide, carboplatin, imatinib, vincristine, and doxorubicin.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number475488-23-4
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