MMP-9/MMP-13 Inhibitor I

Code: 444252-1MG D2-231

Biochem/physiol Actions

Target IC50: 900 pM against both MMP-9 and MMP-13

Reversible: no

Product does not compete with ATP.

Cell permeable: yes

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Your Price
€139.80 1MG
€139.80 inc. VAT

Biochem/physiol Actions

Target IC50: 900 pM against both MMP-9 and MMP-13

Reversible: no

Product does not compete with ATP.

Cell permeable: yes

Primary TargetMMP-9

General description

A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC50 = 900 pM) and MMP-13 (IC50 = 900 pM). Inhibits MMP-1 and MMP-3 at much higher concentrations (IC50 = 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50 = 930 nM).

A cell-permeable and highly, piperazine-based potent inhibitor of MMP-9 (IC50 = 900 pM) and MMP-13 (IC50 = 900 pM). Inhibits MMP-1 and MMP-3 at much higher concentrations (IC50 = 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50 = 930 nM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Cheng, M., et al. 2000. J. Med. Chem.43, 369.

Packaging

1 mg in Plastic ampoule

Packaged under inert gas

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)

assay≥95% (HPLC)
colorwhite
formsolid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitymethanol: 1 mg/mL, DMSO: 100 mg/mL
storage conditionprotect from light, OK to freeze
storage temp.−20°C
Cas Number204140-01-2
This product has met the following criteria to qualify for the following awards:



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