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General description

Hydrogen peroxide (H₂O₂) is involved in therapeutic processes such as wound healing, anti-bacterial defense, stem cell proliferation, and an adaptive response in astrocytes that leads to neuronal protection. However, over-production of H₂O₂ exerts toxic effects on the cell and its surrounding environment. Over-production of H₂O₂ is connected to serious pathological conditions such as cancer, ageing, diabetes, and neurodegenerative diseases.BioTracker Green H₂O₂ live cell dye is a fluorescent probe that fluoresces upon reaction with H₂O₂ , but does not react with other ROS such as hydroxyradical (-OH), superoxide (O2-), hypochlorous acid (HOCl), singlet oxygen (¹O₂), and nitric oxide (NO). This dye is cell permeable and initially has low reactivity with H₂O₂ but it is quickly hydrolyzed by intracellular esterases to generate a reactive and cell impermeable product that fluoresces upon reaction with H₂O₂. Spectral PropertiesAbsorbance (max): 492 nmEmission (max): 516 nm (Green)Research Categories:InflammationLive Cell Dye