Analysis Note

Color (visual): white to slight yellowAppearance of substance (visual): powderIdentity (IR): passes testPurity (TLC(0811)): ≥ 98 %Assay (HPLC, area%): ≥ 95.0 % (a/a)Assay (acidimetric): ≥ 90.0 %Water (K. F.): ≤ 2.00 %For TLC-Systems see our General Catalog

General description

The use of this derivative was found to be essential for the synthesis of peptides related to nucleolin [1].

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP^®/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.

The product number for this product was previously 04-12-1266.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-12-1266