Application

Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate was reported to chemoselectively modify histidine under visible light where the unsubstituted nitrogen groups on the modified His imidazole are conserved. Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate is also a versitile reagent for photoredox chemistry.

Other Notes

Histidine-specific peptide modification via visible-light-promoted C-H alkylationOpen-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library SynthesisA photocatalyst-free photo-induced denitroalkylation of ß-nitrostyrenes with 4-alkyl substituted Hantzsch esters at room temperatureIntermolecular Radical Addition to Ketoacids Enabled by Boron ActivationOxa- and Azabenzonorbornadienes as Electrophilic Partners under Photoredox/Nickel Dual CatalysisExploration of a chiral cobalt catalyst for visible-light-induced enantioselective radical conjugate addition