Application
The human D-dimer protein is a blood test performed in the medical laboratory to diagnose thrombosis. While a negative human D-dimer result rules out thrombosis, a positive test result can indicate thrombosis or other underlying potential health problems. The presence of D-dimer can idicate the existance of a deep venous thrombosis (DVT) or pulomonary embolism (PE).
General description
The human D-dimer(s) protein is an indicator of a thrombosis event. This protein is the degradation fragment of fibrin mesh that has been stabilized by Factor XIII. This factor crosslinks the E-element to two D-elements. As a result, this crosslink is the final step in the generation of a thrombus.
Physical form
The human D-dimer protein provided in liquid form constisting of 0.05 M sodium phosphate, pH 7.5, 0.15 M sodium chloride and 0.09% sodium azide.
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