Analysis Note

ControlSkin tissue, normal breast epithelium, melanocytes, mast cells and glial cells

Application

Research CategoryStem Cell Research

Flow Cytometry: 0.2 µg per 10e6 cells

Immunoprecipitation

Immunohistochemistry (Frozen)

Western blot

Blocking Ligand Binding

Optimal working dilutions must be determined by the end user.

Detect CD117 using this Anti-CD117 Antibody, clone ACK2 validated for use in FC, IH, IP, FUNC & WB.

Research Sub CategoryHematopoietic Stem CellsMesenchymal Stem Cells

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: CBL1360P

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein A purified

The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide.

Format: Purified

Specificity

Specifically recognizes mouse CD117, known as c-kit receptor, stem cell factor receptor and steel factor receptor.

Storage and Stability

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

Target description

145 kDa